Chlorpromazine induced ocular myasthenia gravis
نویسندگان
چکیده
منابع مشابه
Ocular Manifestations of Myasthenia Gravis
The cause of the weakness is due to a defect at the level of the neuromuscular junction in which autoimmune antibodies block the receptors responsible for initiating muscular contraction. The neurotransmitter that is subject to this competitive inhibition is acetylcholine (ACh). The muscles commonly affected include those of the neck, limbs and chest cavity with regards to breathing. The muscle...
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To the Editors: Myasthenia gravis presents with only ocular symptoms (diplopia, ptosis, and extraocular movement limitation) in approximately 20% of patients.1,2 Ocular myasthenia gravis is to be suspected in patients with intermittent diplopia with ophthalmoplegia that does not correspond to a single ocular motor nerve paresis. However, diplopia in only eccentric sustained gaze in myasthenia g...
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We report a 71-year-old woman with concomitant ocular myasthenia gravis and euthyroid Graves' ophthalmopathy. Unilateral ophthalmoplegia, including ptosis, initially was responsive to edrophonium and corticosteroids, except for diplopia on upward gaze, but refractory swelling of the inferior rectus muscle and proptosis followed. Autoantibodies to acetylcholine and thyrotropin receptors were det...
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A 68-year-old black woman who was put on D-penicillamine therapy (250-500 mg per day, total dose 15 g) for rheumatoid arthritis developed ocular myasthenia gravis. Two weeks after she discontinued D-penicillamine her signs and symptoms cleared with no other treatment. Review of previous cases and possible immunological mechanisms are discussed.
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A 39-year-old woman was diagnosed with myasthenia gravis when she was 8 years old. Although many treatments - such as cholinesterase inhibitors and steroids - had been given to the patient, her condition did not improve sufficiently. As she demonstrated bilateral 3 mm levator function without any eye movement disturbances, bilateral frontalis sling procedures were performed with an autologous f...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2013
ISSN: 2319-2003
DOI: 10.5455/2319-2003.ijbcp20131027